We maintain websites for genetic variants in the human coagulation factors F5, F7, F8, F9, F10, and F11.

    F5 Variants

Factor V (FV) deficiency, FV Leiden, and F5 Atlanta are caused by variants in the F5 gene, which encodes coagulation Factor V. Compiled within this database are 363 unique variants in the F5 gene, corresponding to 801 individual cases.

    Citing Us

Please reference this website by citing the following publication:

  • Efthymiou C, Print EHT, Simmons A, Perkins SJ. Analysis of 363 genetic variants in F5 via an interactive web database reveals new insights into FV deficiency and FV Leiden. 2023 Thromb. Haemost. Open 7: e30-e41. PMID: 36751301

    What can you do in this database?

This website enables readers to investigate all pathogenic variants reported in the F5 gene prior to November 2021. The database includes sequence, structural and statistical information on the variants.

Additionally, there is an online form enabling readers to submit new variants and contribute to the genetic services provided by this website.

For easy navigation across the website, please click for the Site Map.

  Simple Nucleotide Search



  Simple Amino Acid Search



    Nomenclature: HGVS & Legacy  

    Have you or someone you know been diagnosed with a Factor V Disease?  

    Latest Release- Version 1.0 (November 2021)  

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visitors since December 2021.

Factor X Variant Database