Factor V Variant Database

Point Mutations Mapped onto the FV sequence

All amino acids in red-bold font have associated mutations (point) within the database.
More information on each mutation can be obtained by clicking on the respective amino acid.
This display is automatically generated and represents all amino acid point mutations within the F5 gene.

KEY = DOMAINS: Signal Peptide-- A1-- Linker-- A2-- a2 -- B-- a3-- A3 -- C1-- C2

MFPGCPRLWV   LVVLGTSWVG   WGSQGTEAAQ   LRQFYVAAQG   ISWSYRPEPT      50

NSSLNLSVTS   FKKIVYREYE   PYFKKEKPQS   TISGLLGPTL   YAEVGDIIKV      100

HFKNKADKPL   SIHPQGIRYS   KLSEGASYLD   HTFPAEKMDD   AVAPGREYTY      150

EWSISEDSGP   THDDPPCLTH   IYYSHENLIE   DFNSGLIGPL   LICKKGTLTE      200

GGTQKTFDKQ   IVLLFAVFDE   SKSWSQSSSL   MYTVNGYVNG   TMPDITVCAH      250

DHISWHLLGM   SSGPELFSIH   FNGQVLEQNH   HKVSAITLVS   ATSTTANMTV      300

GPEGKWIISS   LTPKHLQAGM   QAYIDIKNCP   KKTRNLKKIT   REQRRHMKRW      350

EYFIAAEEVI   WDYAPVIPAN   MDKKYRSQHL   DNFSNQIGKH   YKKVMYTQYE      400

DESFTKHTVN   PNMKEDGILG   PIIRAQVRDT   LKIVFKNMAS   RPYSIYPHGV      450

TFSPYEDEVN   SSFTSGRNNT   MIRAVQPGET   YTYKWNILEF   DEPTENDAQC      500

LTRPYYSDVD   IMRDIASGLI   GLLLICKSRS   LDRRGIQRAA   DIEQQAVFAV      550

FDENKSWYLE   DNINKFCENP   DEVKRDDPKF   YESNIMSTIN   GYVPESITTL      600

GFCFDDTVQW   HFCSVGTQNE   ILTIHFTGHS   FIYGKRHEDT   LTLFPMRGES      650

VTVTMDNVGT   WMLTSMNSSP   RSKKLRLKFR   DVKCIPDDDE   DSYEIFEPPE      700

STVMATRKMH   DRLEPEDEES   DADYDYQNRL   AAALGIRSFR   NSSLNQEEEE      750

FNLTALALEN   GTEFVSSNTD   IIVGSNYSSP   SNISKFTVNN   LAEPQKAPSH      800

QQATTAGSPL   RHLIGKNSVL   NSSTAEHSSP   YSEDPIEDPL   QPDVTGIRLL      850

SLGAGEFKSQ   EHAKHKGPKV   ERDQAAKHRF   SWMKLLAHKV   GRHLSQDTGS      900

PSGMRPWEDL   PSQDTGSPSR   MRPWKDPPSD   LLLLKQSNSS   KILVGRWHLA      950

SEKGSYEIIQ   DTDEDTAVNN   WLISPQNASR   AWGESTPLAN   KPGKQSGHPK      1000

FPRVRHKSLQ   VRQDGGKSRL   KKSQFLIKTR   KKKKEKHTHH   APLSPRTFHP      1050

LRSEAYNTFS   ERRLKHSLVL   HKSNETSLPT   DLNQTLPSMD   FGWIASLPDH      1100

NQNSSNDTGQ   ASCPPGLYQT   VPPEEHYQTF   PIQDPDQMHS   TSDPSHRSSS      1150

PELSEMLEYD   RSHKSFPTDI   SQMSPSSEHE   VWQTVISPDL   SQVTLSPELS      1200

QTNLSPDLSH   TTLSPELIQR   NLSPALGQMP   ISPDLSHTTL   SPDLSHTTLS      1250

LDLSQTNLSP   ELSQTNLSPA   LGQMPLSPDL   SHTTLSLDFS   QTNLSPELSH      1300

MTLSPELSQT   NLSPALGQMP   ISPDLSHTTL   SLDFSQTNLS   PELSQTNLSP      1350

ALGQMPLSPD   PSHTTLSLDL   SQTNLSPELS   QTNLSPDLSE   MPLFADLSQI      1400

PLTPDLDQMT   LSPDLGETDL   SPNFGQMSLS   PDLSQVTLSP   DISDTTLLPD      1450

LSQISPPPDL   DQIFYPSESS   QSLLLQEFNE   SFPYPDLGQM   PSPSSPTLND      1500

TFLSKEFNPL   VIVGLSKDGT   DYIEIIPKEE   VQSSEDDYAE   IDYVPYDDPY      1550

KTDVRTNINS   SRDPDNIAAW   YLRSNNGNRR   NYYIAAEEIS   WDYSEFVQRE      1600

TDIEDSDDIP   EDTTYKKVVF   RKYLDSTFTK   RDPRGEYEEH   LGILGPIIRA      1650

EVDDVIQVRF   KNLASRPYSL   HAHGLSYEKS   SEGKTYEDDS   PEWFKEDNAV      1700

QPNSSYTYVW   HATERSGPES   PGSACRAWAY   YSAVNPEKDI   HSGLIGPLLI      1750

CQKGILHKDS   NMPMDMREFV   LLFMTFDEKK   SWYYEKKSRS   SWRLTSSEMK      1800

KSHEFHAING   MIYSLPGLKM   YEQEWVRLHL   LNIGGSQDIH   VVHFHGQTLL      1850

ENGNKQHQLG   VWPLLPGSFK   TLEMKASKPG   WWLLNTEVGE   NQRAGMQTPF      1900

LIMDRDCRMP   MGLSTGIISD   SQIKASEFLG   YWEPRLARLN   NGGSYNAWSV      1950

EKLAAEFASK   PWIQVDMQKE   VIITGIQTQG   AKHYLKSCYT   TEFYVAYSSN      2000

QINWQIFKGN   STRNVMYFNG   NSDASTIKEN   QFDPPIVARY   IRISPTRAYN      2050

RPTLRLELQG   CEVNGCSTPL   GMENGKIENK   QITASSFKKS   WWGDYWEPFR      2100

ARLNAQGRVN   AWQAKANNNK   QWLEIDLLKI   KKITAIITQG   CKSLSSEMYV      2150

KSYTIHYSEQ   GVEWKPYRLK   SSMVDKIFEG   NTNTKGHVKN   FFNPPIISRF      2200

IRVIPKTWNQ   SIALRLELFG   CDIY

KEY = DOMAINS: Signal Peptide-- A1-- Linker-- A2-- a2 -- B-- a3-- A3 -- C1-- C2

Factor X Variant Database

Factor V Gene (F5)

Variant Database

Point Mutations Mapped onto the FV sequence

KEY = DOMAINS: Signal Peptide-- A1-- Linker-- A2-- a2 -- B-- a3-- A3 -- C1-- C2

KEY = DOMAINS: Signal Peptide-- A1-- Linker-- A2-- a2 -- B-- a3-- A3 -- C1-- C2