Factor V Variant Database

Terms with a '*' next to them are explained on the Help Page .

c.1334T>C

p.Ile445Thr (Legacy AA No. 417)

Variant Type:

Point

Domain:

d5A2

Location:

Exon 9

Variant Effect:

Missense

Codon Change:

1334T>C

No. of Patients Reported:

Phenotype:

Asymptomatic

Association:

FV Deficiency

Allele Count *:

Allele Number *:

Allele Frequency *:

Kling et al 2006
extreme bleeding after surgery and tooth extractions

Patient_ID	Age (Yrs)	Gender	Race	FV:C(%)	FV:C (IU/dl)	FV:Ag(%)	FV:Ag (IU/dl)	Inheritance	Other Variants	Severity	Comments	Reference
174	NA	M	NA	<5	NA	5	NA	Heterozygous	c.4699_4702dupATTG (p.Ala1568Aspfs*21)	Asymptomatic	extreme bleeding after surgery and tooth extractions	Kling et al 2006
175	NA	F	NA	46	NA	50	NA	Heterozygous		Asymptomatic	NA	Kling et al 2006
527	NA	M	NA	<5	NA	5	NA	Heterozygous	c.4699_4702dupATTG (p.Ala1568Aspfs*21)	Asymptomatic	bleeding following abdominal surgery and tooth removal	Kling et al 2006

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Factor X Variant Database

Factor V Gene (F5)